EPH Receptor A7 Antikörper

Produktnummer ABIN272234

Produktdetails anti-EPH Receptor A7 Antikörper

Target: EPH Receptor A7 (EPHA7)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of EphA7 protein. (region surrounding Glu477)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1/40000-1/60000. Western Blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu EPH Receptor A7

Target: EPH Receptor A7 (EPHA7)

Andere Bezeichnung: EPHA7 (EPHA7 Produkte)

Synonyme: fc51g03 antikoerper, wu:fc51g03 antikoerper, si:dkey-23k6.1 antikoerper, EHK3 antikoerper, HEK11 antikoerper, Cek11 antikoerper, Ebk antikoerper, Ehk3 antikoerper, Hek11 antikoerper, Mdk1 antikoerper, CEPHA7 antikoerper, EPH receptor A7 antikoerper, eph receptor A7 antikoerper, ephrin type-B receptor 1-B antikoerper, Eph receptor A7 antikoerper, EPHA7 antikoerper, epha7 antikoerper, LOC100166161 antikoerper, Epha7 antikoerper

Hintergrund: The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date. The Eph subfamily receptors of human origin (and their murine/avian homologs) include EphA1 (Eph), EphA2 (Eck), EphA3 (Hek4), EphA4 (Hek8), EphA5 (Hek7), EphA6 (Hek12), EphA7 (Hek11/MDK1), EphA8(Hek3), EphB1 (Hek6), EphB2 (Hek5), EphB3 (Cek10, Hek2), EphB4 (Htk), EphB5(Hek9) and EphB6 (Mep). EphAs are a family of receptor tyrosine kinases that are involved in axonal guidance during development. These receptors and their ligands, the ephrins, act via repulsive mechanisms to guide growing axons towards their appropriate targets and allow for the correct developmental connections to be made. Ligand binding to an Eph receptor results in tyrosine phosphorylation of the kinase domain, and repulsion of axonal growth cones and migrating cells. During neurulation, ephrin-A5 is coexpressed with its cognate receptor EphA7 in cells at the edges of the dorsal neural folds. Three different EphA7 splice variants, a full-length form and two truncated versions lacking kinase domains, are expressed in the neural folds.Synonyms: EHK3, EPH homology kinase 3, Ephrin type-A receptor 7, HEK11, Receptor protein-tyrosine kinase HEK11, Tyrosine-protein kinase receptor EHK-3

Molekulargewicht: approx. 112 kDa

Gen-ID: 2045

NCBI Accession: NP_004431

UniProt: Q15375

Pathways: RTK Signalweg