DYRK1A Antikörper

Produktnummer ABIN272227

Produktdetails anti-DYRK1A Antikörper

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYRK1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Dyrk1A protein. (region surrounding Gln39)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 5000. Western blot: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu DYRK1A

Target: DYRK1A (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 1A (DYRK1A))

Andere Bezeichnung: DYRK1A (DYRK1A Produkte)

Synonyme: DYRK1A antikoerper, dyrk antikoerper, dyrk1 antikoerper, hp86 antikoerper, mnb antikoerper, mnbh antikoerper, DYRK antikoerper, DYRK1 antikoerper, HP86 antikoerper, MNB antikoerper, MNBH antikoerper, MRD7 antikoerper, 2310043O08Rik antikoerper, D16Ertd272e antikoerper, D16Ertd493e antikoerper, Dyrk antikoerper, ENSMUSG00000074897 antikoerper, Gm10783 antikoerper, Mnbh antikoerper, Mp86 antikoerper, mmb antikoerper, PSK47 antikoerper, dual specificity tyrosine phosphorylation regulated kinase 1A antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A antikoerper, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a antikoerper, dual specificity tyrosine-(Y)-phosphorylation regulated kinase 1A S homeolog antikoerper, DYRK1A antikoerper, dyrk1a antikoerper, Dyrk1a antikoerper, dyrk1a.S antikoerper

Hintergrund: Dyrk (for dual specificity tyrosine phosphorylation regulated kinase) is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis. Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation. Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases. Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions. Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome.Synonyms: DYRK, Dual specificity YAK1-related kinase, Dual specificity tyrosine-phosphorylation-regulated kinase 1A, HP86, MNB, MNBH, Protein kinase minibrain homolog

Molekulargewicht: approx. 90 kDa

Gen-ID: 1859

NCBI Accession: NP_001387

UniProt: Q13627

Pathways: Mitotic G1-G1/S Phases