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TOP3B Antikörper

TOP3B Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN272153
  • Target Alle TOP3B Antikörper anzeigen
    TOP3B (Topoisomerase (DNA) III beta (TOP3B))
    Reaktivität
    • 35
    • 21
    • 3
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 32
    • 4
    Kaninchen
    Klonalität
    • 33
    • 3
    Polyklonal
    Konjugat
    • 19
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TOP3B Antikörper ist unkonjugiert
    Applikation
    • 29
    • 18
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody detects endogenous levels of Topo IIIbeta-1 protein. (region surrounding Gln84)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, Mouse.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Reinheit
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product TOP3B Primärantikörper
  • Applikationshinweise
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    DO NOT FREEZE!
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C.
  • Target
    TOP3B (Topoisomerase (DNA) III beta (TOP3B))
    Andere Bezeichnung
    TOP3B (TOP3B Produkte)
    Synonyme
    TOP3B1 antikoerper, top3b antikoerper, DNA topoisomerase III beta antikoerper, topoisomerase (DNA) III beta antikoerper, DNA topoisomerase III beta L homeolog antikoerper, TOP3B antikoerper, Top3b antikoerper, top3b.L antikoerper
    Hintergrund
    DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA by transiently breaking and rejoining DNA strands. Although DNA topoisomerase I and DNA topoisomerase II relax both positive and negative supercoils, DNA topoisomerase III relaxes only negative supercoils. DNA topoisomerase III alpha exists as a long and a short isoform, which are produced by alternative splicing. DNA topoisomerase III alpha, which localizes to the nucleolus, is constitutively expressed and remains at high levels throughout the cell cycle in HL-60 cells. DNA topoisomerase III beta exists as three isoforms, namely beta1, beta2 and beta3, also produced by alternative splicing. DNA topoisomerase III beta1 is expressed in testes, heart and skeletal muscle, whereas beta2 is expressed in thymus, kidney and pancreas.Synonyms: DNA topoisomerase 3-beta-1, DNA topoisomerase III beta-1, TOP3B1
    Molekulargewicht
    approx. 96 kDa
    Gen-ID
    8940
    NCBI Accession
    NP_003926
    UniProt
    O95985
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