TOP3B Antikörper

Produktnummer ABIN7075940

Produktdetails anti-TOP3B Antikörper

Target: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Ratte

Aufreinigung: Affinity purification

Immunogen: Recombinant protein corresponding to Mouse TOP3B

Anwendungsinformationen

Applikationshinweise: WB (R) 1:800-1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu TOP3B

Target: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Andere Bezeichnung: TOP3B (TOP3B Produkte)

Synonyme: TOP3B1 antikoerper, top3b antikoerper, DNA topoisomerase III beta antikoerper, topoisomerase (DNA) III beta antikoerper, DNA topoisomerase III beta L homeolog antikoerper, TOP3B antikoerper, Top3b antikoerper, top3b.L antikoerper

Hintergrund: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants.

Molekulargewicht: 97 kDa

Gen-ID: 21976

NCBI Accession: NP_001313505

UniProt: Q9Z321