TOP3B Antikörper (C-Term)

Produktnummer ABIN1537618

Produktdetails anti-TOP3B Antikörper

Target: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Bindungsspezifität: AA 826-854, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TOP3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 826-854 amino acids from the C-terminal region of human TOP3B.

Klon: RB35782

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: TOP3B Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu TOP3B

Target: TOP3B (Topoisomerase (DNA) III beta (TOP3B))

Andere Bezeichnung: TOP3B (TOP3B Produkte)

Synonyme: TOP3B1 antikoerper, top3b antikoerper, DNA topoisomerase III beta antikoerper, topoisomerase (DNA) III beta antikoerper, DNA topoisomerase III beta L homeolog antikoerper, TOP3B antikoerper, Top3b antikoerper, top3b.L antikoerper

Hintergrund: This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity, however, not all variants have been fully described.

Molekulargewicht: 96662

Gen-ID: 8940

NCBI Accession: NP_001269041, NP_001269042, NP_003926

UniProt: O95985