RPS6KA1 Antikörper

Produktnummer ABIN271934

Produktdetails anti-RPS6KA1 Antikörper

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPS6KA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of p90 RSK protein. (region surrounding Thr353)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1000approx. 1: 5000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu RPS6KA1

Target: RPS6KA1 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1))

Andere Bezeichnung: RPS6KA1 (RPS6KA1 Produkte)

Synonyme: HU-1 antikoerper, MAPKAPK1A antikoerper, RSK antikoerper, RSK1 antikoerper, Rsk1 antikoerper, p90rsk antikoerper, rsk antikoerper, RPS6KA antikoerper, hu-1 antikoerper, mapkapk1a antikoerper, rsk1 antikoerper, wu:fc56h07 antikoerper, zgc:152654 antikoerper, ribosomal protein S6 kinase A1 antikoerper, ribosomal protein S6 kinase polypeptide 1 antikoerper, ribosomal protein S6 kinase A1-like antikoerper, ribosomal protein S6 kinase A1 L homeolog antikoerper, ribosomal protein S6 kinase a, polypeptide 1 antikoerper, RPS6KA1 antikoerper, Rps6ka1 antikoerper, RPS6KA1L antikoerper, rps6ka1.L antikoerper, rps6ka1 antikoerper

Hintergrund: The 90 kDa family of ribosomal S6 kinases (Rsks), designated Rsk-1 (MAPKAP kinase-1), Rsk-2 and Rsk-3, are intracellular Serine/Threonine kinases that are important signaling intermediates in response to a broad range of ligand activated receptor tyrosine kinases. A unique feature common to the members of the Rsk family is that each possesses two non-identical complete kinase catalytic domains. An additional Rsk protein, Rsk-4, shows a high level of homology to the three previously isolated members of the human Rsk family. Rsk-4 is most abundantly expressed in brain and kidney and plays a role in normal neuronal development. The 70 kDa family of ribosomal S6 kinases includes p70 S6 kinase and p70 S6 kinase β, which are thought to have similar regulatory functions. MSK1 (also designated RLPK) is a novel Rsk-related protein, which, like the p90 Rsk family members, contains two non-identical complete kinase catalytic domains.Synonyms: 90 kDa ribosomal protein S6 kinase 1, MAPKAPK1A, RSK-1, RSK1, Ribosomal S6 kinase 1, Ribosomal protein S6 kinase alpha-1, p90RSK1

Molekulargewicht: approx. 83 kDa

Gen-ID: 6195

NCBI Accession: NP_001006666

UniProt: Q15418

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades