CD3 Antikörper

Produktnummer ABIN2704232

This anti-CD3 antibody (ABIN2704232) is a Mouse Monoclonal antibody detecting CD3 in FACS. Suitable for Human.

Quick Overview for CD3 Antikörper (ABIN2704232)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Güteklasse: GMP Grade

Klon: OKT3

Produktdetails anti-CD3 Antikörper

Verwendungszweck: CD3 Unconjugated Antibody

Produktmerkmale: CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

Aufreinigung: Purified

Reinheit: >95 %

Immunogen: Human peripheral blood lymphocytes

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

NCBI Accession: NM_000733

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway