AIM2 Antikörper (AA 255-354) (PE)
Kurzübersicht für AIM2 Antikörper (AA 255-354) (PE) (ABIN2690017)
Target
Alle AIM2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 255-354
- 
                                            Kreuzreaktivität
- Human, Maus, Ratte
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from mouse AIM2
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- FCM 1:20-100
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 
                                            Haltbarkeit
- 12 months
 
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- 
    - AIM2 (Absent in Melanoma 2 (AIM2))
- 
                                            Andere Bezeichnung
- AIM2
- 
                                            Hintergrund
- 
                        Synonyms: Gm1313, Ifi210, Interferon-inducible protein AIM2, Interferon-inducible protein 210, Ifi-210, Interferon-inducible protein p210, Aim2 Background: Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8. 
- 
                                            Gen-ID
- 383619
- 
                                            UniProt
- Q91VJ1
- 
                                            Pathways
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
 Target
- 
                    
 
                                     
                                     
                                    