CD79a Antikörper

Produktnummer ABIN2689396

Dieses Anti-CD79a-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CD79a in ICS. Geeignet für Human und Maus. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für CD79a Antikörper (ABIN2689396)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD79a Antikörper ist unkonjugiert

Applikation: Intracellular Staining (ICS)

Klon: HM47

Produktdetails anti-CD79a Antikörper

Marke: BD Pharmingen™

Produktmerkmale: Reacts with the cytoplasmic domain of a 47 kDa membrane glycoprotein present on B lymphocytes, also referred to as mb-1. It is expressed on B cells at various stages of differentiation, from pre-B cell stage, probably before expression of cytoplasmic μ chain, to plasma cell stage, in which it is detected only in the cytoplasm. CD79a associates with CD79b to form part of the B-cell receptor complex. It has been suggested that CD79a may play a role in mediating the transport of IgM to the cell surface. This antibody has been found to react on permeabilized A20 cells (mouse B cell line). Profile of permeabilized peripheral blood lymphocytes with Cytofix/Cytoperm (Cat# 554714) analyzed on a FACScan

BD Pharmingen™ Purified Mouse Anti-Human CD79a - Purified - Clone HM47 - Isotype Mouse IgG1, κ - Reactivity Hu, Ms - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CD79a Antikörper (ABIN2689396)

Mason, Cordell, Tse, van Dongen, van Noesel, Micklem, Pulford, Valensi, Comans-Bitter, Borst: "The IgM-associated protein mb-1 as a marker of normal and neoplastic B cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 147, Issue 11, pp. 2474-82, (1991) (PubMed).

Sakaguchi, Kashiwamura, Kimoto, Thalmann, Melchers: "B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties." in: The EMBO journal, Vol. 7, Issue 11, pp. 3457-64, (1989) (PubMed).

Details zu CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Andere Bezeichnung: CD79a

Hintergrund: Synonyms: Igα, mb-1

Pathways: BCR Signaling