CD55 Antikörper
Kurzübersicht für CD55 Antikörper (ABIN2689337)
Target
Alle CD55 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
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Reacts with CD55, decay-accelerating factor (DAF), a glycosylphosphatidylinositol (GPI)-anchored single chain glycoprotein of approximately 70 kDa, expressed on hematopoietic cells. It has been suggested that the role of DAF is to protect cells from damage by autologous complement preventing the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertases, C4b2a3b and C3bBb3b. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of K562 cells expressing glycosylphosphatidylinositol (GPI) anchor protein analyzed by flow cytometry Profile of glycosylphosphatidylinositol (GPI) anchor-defective mutant cell line analyzed by flow cytometry
BD Pharmingen™ Purified Mouse Anti-Human CD55 - Purified - Clone IA10 - Isotype Mouse IgG2a, κ - Reactivity Hu - 0.1 mg -
Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Isotyp
- IgG2a kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C.
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: "Coordinate functions of multiple complement regulating molecules, CD46, CD55, and CD59." in: Transplantation proceedings, Vol. 26, Issue 3, pp. 1070-1, (1994) (PubMed).
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- CD55 (Complement Decay-Accelerating Factor (CD55))
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Andere Bezeichnung
- CD55
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Hintergrund
- Synonyms: DAF
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Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity
Target
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