CXCR1 Antikörper

Produktnummer ABIN2689039

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-CXCR1 Antikörper (Klon 5A12) (ABIN2689039) detektiert spezifisch CXCR1 in FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CXCR1 Antikörper (ABIN2689039)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCR1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 5A12

Produktdetails anti-CXCR1 Antikörper

Produktmerkmale: Reacts with Interleukin-8 receptor A (IL-8RA), a G protein-linked seven transmembrane domain protein, expressed on monocytes and granulocytes. It is also expressed on a subset of T cells. Both IL-8RA and IL-8RB are high affinity receptors for IL-8. IL-8 is an inflammatory cytokine which induces chemotaxis of neutrophils, basophils and T lymphocytes. IL-8RA and IL-8RB were first clustered as CD128a and CD128b, respectively in the VIIth HLDA workshop, and then were re-clustered as CD181 and CD182, respectively in the VIIIth HLDA workshop. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of peripheral blood granulocytes analyzed by flow cytometry. Second step staining with Cat. No. 555988.

BD Pharmingen™ Purified Mouse Anti-Human CD181 - Purified - Clone 5A12 - Isotype Mouse IgG2b, κ - Reactivity Hu - 0.5 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C.

Referenzen für anti-CXCR1 Antikörper (ABIN2689039)

Qin, LaRosa, Campbell, Smith-Heath, Kassam, Shi, Zeng, Buthcher, Mackay: "Expression of monocyte chemoattractant protein-1 and interleukin-8 receptors on subsets of T cells: correlation with transendothelial chemotactic potential." in: European journal of immunology, Vol. 26, Issue 3, pp. 640-7, (1996) (PubMed).

Baggiolini, Loetscher, Moser: "Interleukin-8 and the chemokine family." in: International journal of immunopharmacology, Vol. 17, Issue 2, pp. 103-8, (1995) (PubMed).

Details zu CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Andere Bezeichnung: CD181

Hintergrund: Synonyms: CXCR1, IL-8RA, CD128a

Pathways: cAMP Metabolic Process