IL2RG Antikörper (Biotin)
Kurzübersicht für IL2RG Antikörper (Biotin) (ABIN2688955)
Target
Alle IL2RG Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
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This antibody reacts with the 65-70 kDa common γ subunit (γc) shared by the IL-2, IL-4, IL-7, IL-9, and IL-15 receptors. The γc receptor is a glycoprotein expressed by most peripheral T and B lymphocytes, NK cells, monocytes, and granulocytes. The cytoplasmic domain of the γc chain plays an important role in cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analysis, the TUGh4 antibody has been shown to specifically recognize human γc expressed by cell lines, including human γc gene-transfected cell lines, which are known to express the human γc chain.
BD Pharmingen™ Biotin Rat Anti-Human CD132 - Biotin - Clone TUGh4 - Isotype Rat IgG2b, κ - Reactivity Hu, Dog - 0.5 mg -
Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Isotyp
- IgG2b kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Aqueous buffered solution containing protein stabilizer and ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store undiluted at 4°C.
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: "Expression of the IL-2 receptor gamma chain on various populations in human peripheral blood." in: International immunology, Vol. 6, Issue 8, pp. 1273-7, (1995) (PubMed).
: "The use of avidin-biotin interaction in immunoenzymatic techniques." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 27, Issue 8, pp. 1131-9, (1979) (PubMed).
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- IL2RG (Interleukin 2 Receptor, gamma (IL2RG))
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Andere Bezeichnung
- CD132
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Pathways
- JAK-STAT Signalweg, Growth Factor Binding
Target
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