C3a Antikörper (Biotin)

Produktnummer ABIN2688861

Produktdetails anti-C3a Antikörper (Biotin)

Target: C3a (Complement Fragment 3a (C3a))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser C3a Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Marke: BD Pharmingen™

Produktmerkmale: The I87-419 antibody reacts with the mouse C3a protein. Anaphylatoxin C3a is a bioactive cleavage product released from plasma component C3 during complement activation and is involved in mediation of a variety of cellular immune responses, as well as being a potent pro-inflammatory agent. The release of this cleavage product is a reliable indicator of in vivo or in vitro complement activation. This antibody is routinely tested by ELISA Detection. Other applications were tested by BD Biosciences Pharmingen during antibody development only or reported in the literature. Representative Mouse C3a standard curve. The curve was generated by a sandwich ELISA using the purified I87-1162 antibody as capture antibody, doubling dilutions of purified mouse C3a protein as standard, and biotinylated I87-419 antibody as detection antibody. The standard curve is displayed as the concentration of purified mouse C3a in ng/mL versus the microwell absorbance.

BD Pharmingen™ Biotin Rat Anti-Mouse C3a - Biotin - Clone I87-419 - Isotype Rat IgG1, κ - Reactivity Ms - 0.1 mg

Aufreinigung: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Klon: I87

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Lagerung: 4 °C

Informationen zur Lagerung: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Referenzen für anti-C3a Antikörper (Biotin) (ABIN2688861)

Hugli: "Structure and function of C3a anaphylatoxin." in: Current topics in microbiology and immunology, Vol. 153, pp. 181-208, (1990) (PubMed).

Hugli: "Structure and function of the anaphylatoxins." in: Springer seminars in immunopathology, Vol. 7, Issue 2-3, pp. 193-219, (1984) (PubMed).

Details zu C3a

Target: C3a (Complement Fragment 3a (C3a))

Andere Bezeichnung: C3a (C3a Produkte)

Synonyme: AHUS5 antikoerper, ARMD9 antikoerper, ASP antikoerper, C3a antikoerper, C3b antikoerper, CPAMD1 antikoerper, AI255234 antikoerper, HSE-MSF antikoerper, Plp antikoerper, C3d antikoerper, complement C3 antikoerper, complement component 3 antikoerper, C3 antikoerper

Pathways: Komplementsystem