IRF3 Antikörper (AA 306-312)
Kurzübersicht für IRF3 Antikörper (AA 306-312) (ABIN2668684)
Target
Alle IRF3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 306-312
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Verwendungszweck
- IRF-3 antibody (pAb)
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Aufreinigung
- Unpurified
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Immunogen
- This IRF-3 antibody was raised against a peptide corresponding to residues 306-312 of human IRF-3.
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Applikationshinweise
- WB: 1:1,000 - 1:2,000 dilution
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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Haltbarkeit
- 24 months
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: "Interferon regulatory factor 3 is involved in Toll-like receptor 4 (TLR4)- and TLR3-induced IL-12p35 gene activation." in: Blood, Vol. 107, Issue 3, pp. 1078-84, (2006) (PubMed).
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- IRF3 (Interferon Regulatory Factor 3 (IRF3))
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Andere Bezeichnung
- IRF-3
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Hintergrund
- IRF-3 (Interferon regulatory factor 3 or IRF3) is a member of the IRF family of transcription factors that include IRF-1, IRF-6 and IRF-7. IRF-3 that has been phosphorylated at serine/threonine forms a complex with CREBBP and translocates to the nucleus to activate transcription of interferon-induced genes.
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Molekulargewicht
- 50 kDa
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Gen-ID
- 3661
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NCBI Accession
- NP_001562
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades
Target
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