IRF5 Antikörper
Kurzübersicht für IRF5 Antikörper (ABIN2666392)
Target
Alle IRF5 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Isotyp
- IgG2b kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- phosphate-buffered solution, pH 7.2, containing 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Upon receipt, store undiluted between 2°C and 8°C.
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- IRF5 (Interferon Regulatory Factor 5 (IRF5))
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Andere Bezeichnung
- IRF5
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Hintergrund
- IRF-5 is a transcription factor belonging to the interferon regulatory factor family. It controls induction of type I IFN genes as well as inflammatory cytokines and chemokines through TLRs and the MyD88-TRAF6 pathway. Several genetic variations of IRF-5 have been reported as a risk factor of Systemic lupus erythematosus (SLE), which is caused by excess IFNα induction.
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Pathways
- TLR Signalweg, Autophagie
Target
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