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PD-1 Antikörper

PDCD1 Reaktivität: Maus FACS, IHC, IF Wirt: Ratte Monoclonal RMP1-14 unconjugated
Produktnummer ABIN2665971
  • Target Alle PD-1 (PDCD1) Antikörper anzeigen
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Reaktivität
    • 160
    • 91
    • 26
    • 5
    • 3
    • 1
    Maus
    Wirt
    • 85
    • 80
    • 41
    • 13
    • 4
    • 2
    • 2
    • 2
    • 1
    Ratte
    Klonalität
    • 164
    • 60
    • 5
    Monoklonal
    Konjugat
    • 115
    • 16
    • 13
    • 13
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PD-1 Antikörper ist unkonjugiert
    Applikation
    • 143
    • 68
    • 52
    • 50
    • 38
    • 20
    • 13
    • 13
    • 13
    • 11
    • 11
    • 11
    • 10
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Marke
    Ultra-LEAF™
    Aufreinigung
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    Klon
    RMP1-14
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product PDCD1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Konservierungsmittel
    Azide free
    Handhabung
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Andere Bezeichnung
    CD279 (PDCD1 Produkte)
    Hintergrund
    CD279 is a 50-55 kD immunoglobulin superfamily member, also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production costimulated by macrophages (but not by dendritic cells and B cells).
    Pathways
    Cancer Immune Checkpoints
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