CD40 Ligand Antikörper
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- Target Alle CD40 Ligand (CD40LG) Antikörper anzeigen
- CD40 Ligand (CD40LG)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD40 Ligand Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Marke
- Ultra-LEAF™
- Kreuzreaktivität
- Cynomolgus, Rhesusaffen
- Aufreinigung
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Klon
- 24-31
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD40LG Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Konservierungsmittel
- Azide free
- Handhabung
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD40 Ligand (CD40LG)
- Andere Bezeichnung
- CD154 (CD40LG Produkte)
- Hintergrund
- CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
- Pathways
- NF-kappaB Signalweg, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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