KIT Antikörper
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- Target Alle KIT Antikörper anzeigen
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser KIT Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Marke
- Ultra-LEAF™
- Aufreinigung
- The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
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Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.
- Klon
- ACK2
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product KIT Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Konservierungsmittel
- Azide free
- Handhabung
- This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
- Andere Bezeichnung
- CD117 (KIT Produkte)
- Hintergrund
- CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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