SPHK1 Antikörper

Produktnummer ABIN2665362

Dieser Maus Monoklonal Antikörper detektiert spezifisch SPHK1 in FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für SPHK1 Antikörper (ABIN2665362)

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SPHK1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Klon: 1A5SC

Produktdetails anti-SPHK1 Antikörper

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu SPHK1

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung: SPHK1

Hintergrund: SPHK1 is a lipid kinase that catalyzes the phosphorylation of sphingosine to sphingosine-1-phosphate (S1P) which is a key sphingolipid signaling molecule involved in cell growth, survival, differentiation, and motility. As an important regulator of ceramide, sphingosine, and S1P, SPHK1 plays important roles in immunological, inflammatory diseases, and cancer. SPHK1 is overexpressed in various types of cancers, and upregulation of SPHK1 has been associated with tumor angiogenesis and resistance to radiation and chemotherapy. Agents targeting the SPHK1 have the potential as therapeutics for cancer, immunological, and inflammatory disorders.

Pathways: VEGF Signaling