Galectin 3 Antikörper (AA 151-251)

Produktnummer ABIN2665254

Der Maus Monoklonal Anti-Galectin 3-Antikörper wurde für IP validiert. Er ist geeignet, Galectin 3 in Proben von Human und Maus zu detektieren.

Kurzübersicht für Galectin 3 Antikörper (AA 151-251) (ABIN2665254)

Target: Galectin 3 (LGALS3)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Galectin 3 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP)

Klon: Gal397

Produktdetails anti-Galectin 3 Antikörper

Bindungsspezifität: AA 151-251

Aufreinigung: The antibody was purified by affinity chromatography.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Mac-2

Substanzklasse: Chemical

Hintergrund: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Pathways: RTK Signalweg