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IL-10 Antikörper

IL10 Reaktivität: Human FACS Wirt: Ratte Monoclonal JES3-19F1 unconjugated

Produktnummer ABIN2665097

Datenblatt (PDF)

Target Alle IL-10 (IL10) Antikörper anzeigen

IL-10 (IL10) (Interleukin 10 (IL10))
Reaktivität
150

92

50

19

16

11

8

7

7

6

5

5

4

2

2

1

1

1

1

1
Human
Wirt
120

77

66

4

2

1
Ratte
Passende Sekundärantikörper
Klonalität
146

121

1
Monoklonal
Konjugat
164

33

12

11

10

5

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
Dieser IL-10 Antikörper ist unkonjugiert
Applikation
165

127

74

65

43

30

28

19

16

15

14

14

14

12

10

9

8

7

7

4

4

4

4

3

2

2

2

2

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Aufreinigung

The antibody was purified by affinity chromatography.

Klon

JES3-19F1

Isotyp

IgG2a kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung

IL-10 (IL10 Produkte)

Hintergrund

IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80 % sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production. The JES3-19F1 antibody reacts with human and viral interleukin-10 (IL-10). The JES3-19F1 antibody can neutralize the bioactivity of natural or recombinant IL-10.

Pathways

Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints