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PD-1 Antikörper

Name: PD-1 Antikörper
SKU: ABIN2664492
Price: 198.79 EUR
Availability: InStock

PDCD1 Reaktivität: Maus FACS Wirt: Ratte Monoclonal 29F-1A12 unconjugated

FACS

2 Abbildungen

Produktnummer ABIN2664492

Datenblatt (PDF)

Target Alle PD-1 (PDCD1) Antikörper anzeigen

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
Reaktivität
161

92

26

5

3

1
Maus
Wirt
85

81

42

13

4

2

2

2

1
Ratte
Passende Sekundärantikörper
Klonalität
166

60

5
Monoklonal
Konjugat
117

16

13

13

7

6

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser PD-1 Antikörper ist unkonjugiert
Applikation
144

68

52

51

39

20

13

13

13

11

11

11

10

7

6

5

4

4

4

4

3

3

2

2

2

1

1

1

1

1

1
Flow Cytometry (FACS)

Aufreinigung

The antibody was purified by affinity chromatography.

Klon

29F-1A12

Isotyp

IgG2a kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C.
Target

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Andere Bezeichnung

CD279 (PDCD1 Produkte)

Hintergrund

CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.

Pathways

Cancer Immune Checkpoints