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NGFR Antikörper

NGFR Reaktivität: Human FACS Wirt: Maus Monoclonal ME20-4 unconjugated
Produktnummer ABIN2664472
  • Target Alle NGFR Antikörper anzeigen
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Reaktivität
    • 162
    • 65
    • 57
    • 28
    • 26
    • 26
    • 25
    • 21
    • 11
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 87
    • 82
    • 4
    • 1
    Maus
    Klonalität
    • 100
    • 74
    Monoklonal
    Konjugat
    • 87
    • 14
    • 12
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NGFR Antikörper ist unkonjugiert
    Applikation
    • 94
    • 88
    • 57
    • 49
    • 42
    • 28
    • 27
    • 20
    • 17
    • 15
    • 15
    • 12
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Kreuzreaktivität
    Affe, Raccoon (Procyon lotor), Schaf, Katze, Hund, Schwein, Kaninchen
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    ME20-4
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product NGFR Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    NGFR (Nerve Growth Factor Receptor (NGFR))
    Andere Bezeichnung
    CD271 (NGFR Produkte)
    Hintergrund
    CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.
    Pathways
    NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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