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IGF1R Antikörper

IGF1R Reaktivität: Human FACS Wirt: Maus Monoclonal 1H7-CD221 unconjugated
Produktnummer ABIN2664409
  • Target Alle IGF1R Antikörper anzeigen
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Reaktivität
    • 193
    • 111
    • 94
    • 16
    • 8
    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 173
    • 33
    • 2
    • 1
    • 1
    Maus
    Klonalität
    • 175
    • 35
    Monoklonal
    Konjugat
    • 129
    • 9
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Dieser IGF1R Antikörper ist unkonjugiert
    Applikation
    • 132
    • 72
    • 64
    • 61
    • 33
    • 26
    • 18
    • 13
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    1H7-CD221
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IGF1R Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Andere Bezeichnung
    CD221 (IGF1R Produkte)
    Hintergrund
    CD221, also known as insulin-like growth factor 1 receptor (IGF1R), is a 135 kD transmembrane receptor. It is widely expressed on lymphoid and myeloid cells as well as non-haematopoietic cells. CD221 is a tyrosine kinase receptor and the ligands for CD221 are insulin-like growth factor 1 and 2 (IGF-1 and IGF-2), the polypeptide hormones similar in molecular structure to insulin. IGF-1/2 binding activates downstream PI3K and MAPK pathways and plays an important role in cell growth. Recent studies reveal its function of recruiting immune cells during tissue repair.
    Pathways
    RTK Signalweg, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagie
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