Insulin Receptor Antikörper
-
- Target Alle Insulin Receptor (INSR) Antikörper anzeigen
- Insulin Receptor (INSR)
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Insulin Receptor Antikörper ist unkonjugiert
-
Applikation
- Intracellular Flow Cytometry (ICFC)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- B6-220
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product INSR Primärantikörper
-
anti-Insulin Receptor (INSR) antibody
INSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C19 unconjugated
anti-Insulin Receptor (INSR) (AA 1024-1298) antibodyINSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1027-1364) antibodyINSR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1101-1372) antibodyINSR Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyINSR Reaktivität: Human, Maus, Ratte, Hund, Affe, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein, Huhn, Schaf, Hamster, Avian, Cat, Esel, Ziege WB Wirt: Ziege Polyclonal unconjugated
anti-Insulin Receptor (INSR) (C-Term) antibodyKO Validated INSR Reaktivität: Human WB, ICC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 1325-1358) antibodyINSR Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB50340 unconjugated
anti-Insulin Receptor (INSR) (AA 1023-1298) antibodyINSR Reaktivität: Human IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 51-150) antibodyINSR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Insulin Receptor (INSR) (AA 27-57), (N-Term) antibodyINSR Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB1421 unconjugated
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
- Target
- Insulin Receptor (INSR)
- Andere Bezeichnung
- CD220 (INSR Produkte)
- Hintergrund
- CD220, also known as insulin receptor, is a type I transmembrane receptor tyrosine kinase composed of two extracellular α-subunits and two transmembrane β-subunits. Binding insulin, the insulin receptor forms a heterotetramer of two units to induce autophosphorylation and activation of the tyrosine kinase activity of the receptor. Activation of insulin receptor leads to subsequent downstream signaling in metabolic regulation, inducing glucose uptake, cell growth, differentiation, and apoptosis. Gene mutation in the insulin receptor or decreased insulin receptor signaling leads to insulin-resistant diabetes mellitus and noninsulin-dependent diabetes mellitus (diabetes mellitus type 2). Most normal cells constitutively express insulin receptors. In hematopoietic cells, insulin receptor is constitutively expressed on monocytes and selectively expressed on activated lymphocytes.
- Pathways
- NF-kappaB Signalweg, RTK Signalweg, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
-
