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Sialoadhesin/CD169 Antikörper

SIGLEC1 Reaktivität: Human FACS Wirt: Maus Monoclonal 7-239 unconjugated
Produktnummer ABIN2664285
  • Target Alle Sialoadhesin/CD169 (SIGLEC1) Antikörper anzeigen
    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
    Reaktivität
    • 46
    • 24
    • 19
    • 4
    • 3
    Human
    Wirt
    • 36
    • 18
    • 18
    • 4
    Maus
    Klonalität
    • 37
    • 36
    • 1
    Monoklonal
    Konjugat
    • 32
    • 9
    • 9
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Sialoadhesin/CD169 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 31
    • 22
    • 20
    • 15
    • 13
    • 13
    • 13
    • 10
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    The antibody was purified by affinity chromatography.
    Klon
    7-239
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product SIGLEC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))
    Andere Bezeichnung
    CD169 (SIGLEC1 Produkte)
    Hintergrund
    CD169, also known as Siglec-1 and Sialoadhesin (Sn), is a 210 kD type I single membrane-spanning glycoprotein. It is the largest member of the Siglec family, consisting of 1709 amino acids and belonging to the immunoglobulin superfamily. CD169 is expressed by macrophages and dendritic cells. By its affinity to α2,3-linked sialic acid, it is involved in macrophage binding to different cell types such as granulocytes, monocytes, NK, B and T cells. Several CD169 counter receptors, such as CD227 on human breast cancer cells, CD43 on T cells and CD206 on macrophages, have been reported.
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