ITGAL Antikörper
Kurzübersicht für ITGAL Antikörper (ABIN2664157)
Target
Alle ITGAL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- The antibody was purified by affinity chromatography.
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 0.5 mg/mL
-
Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
-
-
- ITGAL (Integrin alpha-L (ITGAL))
-
Andere Bezeichnung
- CD11a/CD18
-
Hintergrund
- CD11/CD18 belongs to the integrin family of proteins. It is heterodimeric cell surface receptor expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocyte adhesion. CD11/CD18 complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. Clone m24 binds the extended/open high affinity conformation of CD11a/CD18. The antibody can be used as a reporter of the activation state of the integrin receptor in response to exposure to Mg2+ or Mn2+.
-
Pathways
- Activated T Cell Proliferation, Integrin Complex
Target
-