Galectin 3 Antikörper (AA 151-251) (PE)

Produktnummer ABIN2663838

Produktdetails anti-Galectin 3 Antikörper (PE)

Target: Galectin 3 (LGALS3)

Bindungsspezifität: AA 151-251

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Galectin 3 Antikörper ist konjugiert mit PE

Applikation: Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: Gal397

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Mac-2 (LGALS3 Produkte)

Synonyme: CBP 35 antikoerper, Gal-3 antikoerper, Galectin-3 antikoerper, leg3 antikoerper, galactoside-binding antikoerper, galectin-3 antikoerper, lectin antikoerper, soluble antikoerper, CBP35 antikoerper, GAL3 antikoerper, GALBP antikoerper, GALIG antikoerper, L31 antikoerper, LGALS2 antikoerper, MAC2 antikoerper, MGC52947 antikoerper, MGC75803 antikoerper, LGALS3 antikoerper, gal-3 antikoerper, GBP antikoerper, L-34 antikoerper, Mac-2 antikoerper, gal3 antikoerper, galectin 3 antikoerper, Galectin-3 antikoerper, avian beta-defensin 3 antikoerper, lectin, galactoside-binding, soluble, 3 L homeolog antikoerper, lectin, galactoside-binding, soluble, 3 antikoerper, galectin 2 antikoerper, lectin, galactose binding, soluble 3 antikoerper, LGALS3 antikoerper, leg3 antikoerper, AvBD3 antikoerper, lgals3.L antikoerper, lgals3 antikoerper, LGALS2 antikoerper, Lgals3 antikoerper

Substanzklasse: Chemical

Hintergrund: Galectin-3 (galactose-specific lectin 3) is a 30-32 kD glycoprotein, also know as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and εBP. It is a member of animal β-galactoside-binding protein family that is expressed in cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells. Galectin-3 contains carbohydrate recognition domains and binds to β-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66. Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis. Galectin-3 structurely possesses NWGR motif that is conserved in BH-1 domain of BCL-2 family and functions as an anti-apoptotic molecule.

Pathways: RTK Signalweg