DLL4 Antikörper (PE)

Produktnummer ABIN2663679

Der PE-konjugierte Hamster Monoklonal anti-DLL4 Antikörper (Klon HMD4-1) (ABIN2663679) detektiert spezifisch DLL4 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Maus.

Kurzübersicht für DLL4 Antikörper (PE) (ABIN2663679)

Target: DLL4 (delta-Like 4 (DLL4))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser DLL4 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: HMD4-1

Produktdetails anti-DLL4 Antikörper (PE)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Andere Bezeichnung: delta-Like 4

Hintergrund: The Notch receptors and their ligands are highly conserved from invertebrates to mammals. Delta-like 4 (DLL4) is one of four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling processes. DLL4 is reported to be essential for the regulation of angiogenesis. In thymus, DLL4 is an essential Notch1 ligand responsible for T cell lineage commitment.

Pathways: Notch Signalweg