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NGFR Antikörper (PE)

Dieses Anti-NGFR-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von NGFR in FACS und ICFC. Geeignet für Human.
Produktnummer ABIN2663264

Kurzübersicht für NGFR Antikörper (PE) (ABIN2663264)

Target

Alle NGFR Antikörper anzeigen
NGFR (Nerve Growth Factor Receptor (NGFR))

Reaktivität

  • 207
  • 63
  • 54
  • 39
  • 30
  • 28
  • 27
  • 22
  • 12
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 110
  • 104
  • 4
  • 1
Maus

Klonalität

  • 143
  • 76
Monoklonal

Konjugat

  • 98
  • 18
  • 12
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NGFR Antikörper ist konjugiert mit PE

Applikation

  • 117
  • 94
  • 88
  • 59
  • 44
  • 43
  • 28
  • 27
  • 21
  • 17
  • 15
  • 15
  • 12
  • 7
  • 7
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon

ME20-4
  • Kreuzreaktivität

    Affe, Raccoon (Procyon lotor), Schaf, Katze, Hund, Schwein, Kaninchen

    Aufreinigung

    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Protect from prolonged exposure to light. Do not freeze.

    Lagerung

    4 °C

    Informationen zur Lagerung

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target

    NGFR (Nerve Growth Factor Receptor (NGFR))

    Andere Bezeichnung

    CD271

    Hintergrund

    CD271, also known as p75NTR, TNFRSF16, p75(NTR), Gp80-LNGFR, and NGFR, is a type I transmembrane protein with a MW of 75 kD. It is expressed by many cell types including neurons, Schwann cells, mesenchymal stem/stromal cells, follicular dendritic cells and melanocytes. The extracellular portion contains four TNFR-Cys repeats that form the binding domain for its ligands (NGF, BDNF, NTF3, and NTF4). The intracellular portion of CD271 contains a death domain, which interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9, to promote cell apoptosis, and to regulate cell differentiation and neurogenesis.

    Pathways

    NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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