CXCR1 Antikörper (FITC)

Produktnummer ABIN2661541

Produktdetails anti-CXCR1 Antikörper (FITC)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCR1 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Klon: 8F1-CXCR1

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Andere Bezeichnung: CD181 (CXCR1 Produkte)

Synonyme: C-C antikoerper, C-C-CKR-1 antikoerper, CD128 antikoerper, CD181 antikoerper, CDw128a antikoerper, CKR-1 antikoerper, CMKAR1 antikoerper, IL8R1 antikoerper, IL8RA antikoerper, IL8RBA antikoerper, Il8ra antikoerper, CXCR-1 antikoerper, IL-8RA antikoerper, CXCR2 antikoerper, IL8RB antikoerper, cxcr1 antikoerper, cxcr2 antikoerper, C-X-C motif chemokine receptor 1 antikoerper, chemokine (C-X-C motif) receptor 1 antikoerper, C-X-C chemokine receptor type 1 antikoerper, C-X-C motif chemokine receptor 1 S homeolog antikoerper, CXCR1 antikoerper, Cxcr1 antikoerper, LOC100461947 antikoerper, cxcr1.S antikoerper

Hintergrund: CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor that belongs to the G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower than that of CXCR2. CXCR1 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α(CXCL1).

Pathways: cAMP Metabolic Process