Der PE-Cy5-konjugierte Ratte Monoklonal anti-IL21 Receptor Antikörper (Klon 4A9) (ABIN2659037) detektiert spezifisch IL21 Receptor in IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Maus.
The antibody was purified by affinity chromatography, and conjugated with PE/Cy5 under optimal conditions. The solution is free of unconjugated PE/Cy5 and unconjugated antibody.
The IL-21R is a member of the cytokine receptor family that closely resembles IL-2R beta and IL-4R alpha. IL-21R is expressed by all mature lymphocytes and up-regulated after B and/or T cell activation, with the highest expression by activated B cells. A functional IL-21R consists of the IL-21R subunit and the commone gamma-chaiin. Upon binding to IL-21, it activates Jak-1, Jak-3, STAT1, STAT3 and STAT 5 transduction pathway.