CXCR7 Antikörper (APC)

Produktnummer ABIN2658746

Dieses Anti-CXCR7-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CXCR7 in FACS und ICFC. Geeignet für Human und Maus.

Kurzübersicht für CXCR7 Antikörper (APC) (ABIN2658746)

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CXCR7 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon: 8F11-M16

Produktdetails anti-CXCR7 Antikörper (APC)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Andere Bezeichnung: CXCR7

Hintergrund: CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and other cell types.

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling