IL2RG Antikörper (APC)

Produktnummer ABIN2658475

Der Ratte-Monoklonal Anti-IL2RG-Antikörper wurde für FACS validiert. Er ist geeignet zum Nachweis von IL2RG in Proben aus Maus. }

Kurzübersicht für IL2RG Antikörper (APC) (ABIN2658475)

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL2RG Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS)

Klon: TUGm2

Produktdetails anti-IL2RG Antikörper (APC)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Andere Bezeichnung: CD132

Hintergrund: CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Pathways: JAK-STAT Signalweg, Growth Factor Binding