DLL4 Antikörper (APC)

Produktnummer ABIN2658301

Der Maus Monoklonal Anti-DLL4-Antikörper wurde für ICFC validiert. Er ist geeignet, DLL4 in Proben von Human zu detektieren.

Kurzübersicht für DLL4 Antikörper (APC) (ABIN2658301)

Target: DLL4 (delta-Like 4 (DLL4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DLL4 Antikörper ist konjugiert mit APC

Applikation: Intracellular Flow Cytometry (ICFC)

Klon: MHD4-46

Produktdetails anti-DLL4 Antikörper (APC)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Andere Bezeichnung: delta-Like Protein 4

Hintergrund: Delta-like protein 4 (DLL4) is a type I transmembrane protein whose extracellular domain contains a DSL domain and eight tandem EGF repeats. After binding of its ligands Notch 1 and Notch 4, the extracellular and cytoplasmic domains are cleaved and the cytoplasmic domain is translocated into the nucleus. DLL4 is expressed in the vascular endothelium, neural epithelium, adrenal cortex, spleen, and lymph nodes. It is also highly expressed in some types of bladder, breast, and renal carcinomas. DLL4 is critical in vascular development and homeostasis.

Pathways: Notch Signalweg