IL3RA Antikörper (Alexa Fluor 647)

Produktnummer ABIN2657123

Dieses Anti-IL3RA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL3RA in FACS und ICFC. Geeignet für Human.

Kurzübersicht für IL3RA Antikörper (Alexa Fluor 647) (ABIN2657123)

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL3RA Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Klon: 6H6

Produktdetails anti-IL3RA Antikörper (Alexa Fluor 647)

Kreuzreaktivität: Rhesusaffen

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu IL3RA

Target: IL3RA (Interleukin 3 Receptor, alpha (IL3RA))

Andere Bezeichnung: CD123

Hintergrund: CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity, when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Pathways: JAK-STAT Signalweg