Cytokeratin 18 Antikörper (Alexa Fluor 594)
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- Target Alle Cytokeratin 18 (KRT18) Antikörper anzeigen
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cytokeratin 18 Antikörper ist konjugiert mit Alexa Fluor 594
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Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions. The solution is free of unconjugated Alexa Fluor® 594.
- Klon
- DA-7
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product KRT18 Primärantikörper
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anti-Keratin 18 (KRT18) antibody
KRT18 Reaktivität: Human WB, FACS, ELISA, IHC (p), IP, ICC Wirt: Maus Monoclonal DC-10 unconjugated
anti-Keratin 18 (KRT18) antibodyKRT18 Reaktivität: Säugetier WB, FACS, ELISA, IHC (p), IP, ICC Wirt: Maus Monoclonal C-04 unconjugated
anti-Keratin 18 (KRT18) (AA 53-150) antibodyKRT18 Reaktivität: Human, Maus, Ratte, Schwein WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 1-423) antibodyKRT18 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 238-396) antibodyKRT18 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C2 unconjugated
anti-Keratin 18 (KRT18) (AA 72-380) antibodyKRT18 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 102-396) antibodyKRT18 Reaktivität: Human WB, IHC, IF, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Keratin 18 (KRT18) (AA 401-430), (C-Term) antibodyKRT18 Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB18746 unconjugated
anti-Keratin 18 (KRT18) (AA 1-430) antibodyKRT18 Reaktivität: Human WB, IF, ELISA, IHC (p), IP Wirt: Maus Monoclonal 2F8 unconjugated
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from prolonged exposure to light. Do not freeze.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C
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- Target
- Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
- Andere Bezeichnung
- Cytokeratin 18 (KRT18 Produkte)
- Hintergrund
- Cytokeratin 18, also known as keratin 18, is a type I intermediate filament protein with a molecular weight of approximately 48 kD. Cytokeratin 18 is a heterotetramer composed of two type I and two type II keratins. Cytokeratin 18 associates with cytokeratin 8 and is widely expressed in simple epithelial tissues in adults, where it is found in the cytoplasm, nucleus, and nucleolus. Cytokeratin 18 is associated with the cytoskeleton and mutations in this protein have been associated with liver disease after environmental insult. Cytokeratin 18 can be modified by glycosylation, phosphorylation (Ser34 and Ser53), acetylation (Ser2), and proteolytic cleavage at amino acids 238 and 397 by caspase family members. The cytokeratin 18 protein interacts with a number of proteins including caspase 3, 14-3-3 gamma, 14-3-3 zeta, 14-3-3 sigma 14-3-3 beta, 14-3-3 eta, keratin 5, keratin 8, TNF receptor II, plakophilin 2, EGF receptor, and usherin, among others.
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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