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Integrin beta 2 Antikörper (Alexa Fluor 594)

Name: Integrin beta 2 Antikörper (Alexa Fluor 594)
SKU: ABIN2656819
Price: 375.17 EUR
Availability: InStock

ITGB2 Reaktivität: Maus FACS Wirt: Ratte Monoclonal M18-2 Alexa Fluor 594

FACS

Immunofluorescence (IF) image for anti-Integrin beta 2 (ITGB2) antibody (Alexa Fluor 594) (ABIN2656819) (Integrin beta 2 Antikörper (Alexa Fluor 594))

2 Abbildungen

Produktnummer ABIN2656819

Datenblatt (PDF)

Target Alle Integrin beta 2 (ITGB2) Antikörper anzeigen

Integrin beta 2 (ITGB2)
Reaktivität
197

59

43

9

7

3

3

3

2

2

2

2

2

2

2

1

1
Maus
Wirt
99

93

41

2

1

1
Ratte
Passende Sekundärantikörper
Klonalität
143

89

2
Monoklonal
Konjugat
107

23

21

16

9

5

4

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
Dieser Integrin beta 2 Antikörper ist konjugiert mit Alexa Fluor 594
Applikation
137

84

56

47

39

33

31

26

26

25

22

12

12

4

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS)

Aufreinigung

The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 594 under optimal conditions. The solution is free of unconjugated Alexa Fluor® 594.

Klon

M18-2

Isotyp

IgG2a kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from prolonged exposure to light. Do not freeze.

Lagerung

4 °C

Informationen zur Lagerung

The antibody solution should be stored undiluted between 2°C and 8°C
Target

Integrin beta 2 (ITGB2)

Andere Bezeichnung

CD18 (ITGB2 Produkte)

Hintergrund

CD18 is a 95 kD protein, also known as integrin β2 subunit. It is expressed on all leukocytes. CD18, in association with integrin α chain CD11a, CD11b, and CD11c forms LFA-1, Mac-1, and αXβ2, respectively, and plays an important role in leukocytes adhesion. The CD18 integrin complexes bind ICAM-1 (CD54), ICAM-2 (CD102), ICAM-3 (CD50), iC3b, and fibrinogen. The M18/2 antibody is able to block tumor cell metastasis and enhance cell adhesion.

Pathways

NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation