Ephrin B3 Antikörper

Produktnummer ABIN265403

Der Kaninchen Polyklonal anti-Ephrin B3 Antikörper wird verwendet zum Nachweis von Ephrin B3 in Proben von Maus, Human und Ratte. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Ephrin B3 Antikörper (ABIN265403)

Target: Ephrin B3 (EFNB3)

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Ephrin B3 Antikörper

Spezifität: This antibody detects endogenous levels of Ephrin-B3 protein. (region surrounding Trp251)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Ephrin B3

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: Ephrin-B3

Hintergrund: Ephrins are the ligands which bind to the Eph receptor subfamily, the largest group of the receptor tyrosine kinase family. Both ephrins and Eph receptors are broadly expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. Two classes of ephrins exist: Class A ephrins are tethered to the membrane by a GPI linkage and bind primarily to EphA receptors, Class B ephrins contain a membrane-spanning region and bind predominantly to EphB receptors.Synonyms: EFNB3, ELK-L3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, EPLG8, LERK-8, LERK8

Molekulargewicht: approx. 36 kDa

Gen-ID: 1949

NCBI Accession: NP_001397

UniProt: Q15768

Pathways: RTK Signalweg