Ephrin B3 Antikörper (AA 221-270)

Produktnummer ABIN1533263

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Ephrin B3 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Maus, Human und Ratte.

Kurzübersicht für Ephrin B3 Antikörper (AA 221-270) (ABIN1533263)

Target: Ephrin B3 (EFNB3)

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ephrin B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Ephrin B3 Antikörper

Bindungsspezifität: AA 221-270

Verwendungszweck: Ephrin-B3 Antibody

Spezifität: Ephrin-B3 Polyclonal Antibody detects endogenous levels of Ephrin-B3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human EFNB3. AA range:221-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu Ephrin B3

Target: Ephrin B3 (EFNB3)

Andere Bezeichnung: EFNB3

Hintergrund:

Synonyms: EFNB3, EPLG8, LERK8, Ephrin-B3, EPH-related receptor transmembrane ligand ELK-L3, EPH-related receptor tyrosine kinase ligand 8, LERK-8

Background: EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the

Gene Name: EFNB3

Protein Name: Ephrin-B3

Molekulargewicht: 35 kDa

Gen-ID: 1949

OMIM: 602297

UniProt: Q15768

Pathways: RTK Signalweg