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LY96 Antikörper (Middle Region)

LY96 Reaktivität: Human, Maus, Ratte WB, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN265133
  • Target Alle LY96 Antikörper anzeigen
    LY96 (Lymphocyte Antigen 96 (LY96))
    Bindungsspezifität
    • 8
    • 8
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 56
    • 12
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 41
    • 19
    Kaninchen
    Klonalität
    • 44
    • 16
    Polyklonal
    Konjugat
    • 29
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LY96 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 22
    • 8
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Aufreinigung
    Purified
    Immunogen
    Rabbit polyclonal MD-2 antibody was raised against a peptide corresponding to amino acids near the middle region of human MD-2.
    Isotyp
    IgG
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    Discover our top product LY96 Primärantikörper
  • Applikationshinweise
    Western Blot: 0,5 - 1 μg/mL. Immunohistochemistry. Found in the liver and spleen, the secreted protein Lymphocyte antigen 96/MD-2ooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide (LPS),and with TLR2 in the response to cell wall components from Gram-positive andGram-negative bacteria.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Phosphate buffered saline with 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Target
    LY96 (Lymphocyte Antigen 96 (LY96))
    Andere Bezeichnung
    MD-2 (LY96 Produkte)
    Synonyme
    MD2 antikoerper, ESOP-1 antikoerper, MD-2 antikoerper, ly-96 antikoerper, Ly-96 antikoerper, Md2 antikoerper, lymphocyte antigen 96 antikoerper, LY96 antikoerper, Ly96 antikoerper
    Hintergrund
    MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1 - 3). TLRs are signaling molecules that recognize different pathogenassociated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS (5,6). The specificity of this response is determined by the species of MD-2, e.g., human MD-2 can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4 (7).Synonyms: ESOP-1, ESOP1, LY96, Lymphocyte antigen 96, MD2
    Gen-ID
    9606
    UniProt
    Q9Y6Y9
    Pathways
    TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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