Hexokinase 2 Antikörper (N-Term)

Produktnummer ABIN263918

Der Maus Monoklonal Anti-Hexokinase 2-Antikörper wurde für WB und EIA validiert. Er ist geeignet, Hexokinase 2 in Proben von Human zu detektieren.

Kurzübersicht für Hexokinase 2 Antikörper (N-Term) (ABIN263918)

Target: Hexokinase 2 (HK2)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hexokinase 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 1A7

Produktdetails anti-Hexokinase 2 Antikörper

Bindungsspezifität: AA 1-917, N-Term

Spezifität: This antibody detects Hexokinase 1, 2.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: Hexokinase type II, Muscle form hexokinase, HK2, HKII

Aufreinigung: Protein-G affinity chromatography

Immunogen: Recombinant human Hexokinase 2 (1-917aa) purified from E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1: 1,000 approx. 1: 3,000, 1: 2,000 as starting dilution.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu Hexokinase 2

Target: Hexokinase 2 (HK2)

Andere Bezeichnung: Hexokinase-2

Hintergrund: Hexokinase is the first enzyme in the glycolytic pathway, catalyzing the transfer of a phosphoryl group from ATP to glucose to form glucose-6-phosphate and ADP. In mammals, four distinct enzymes (types 1 to 4 hexokinases) have been identified. These enzymes are found in most cells, but there is tissue specificity for the particular type of hexokinase. Hexokinase 2 is found in the skeletal muscle and includes hydrophobic N-terminal sequence capable of targeting the hexokinase to mitochondria.Synonyms: HK2, HKII, Hexokinase type II, Muscle form hexokinase

Gen-ID: 3099

UniProt: P52789

Pathways: PI3K-Akt Signalweg, Carbohydrate Homeostasis, Warburg Effekt