ATM Antikörper (AA 2577-3056)

Produktnummer ABIN2617305

Der Maus Monoklonal Anti-ATM Antikörper wurde für WB, IHC, IF, IP und IHC (p) validiert. Er ist geeignet, ATM in Proben von Human, Maus, Ratte und Affe zu detektieren.

Kurzübersicht für ATM Antikörper (AA 2577-3056) (ABIN2617305)

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Reaktivität: Human, Maus, Ratte, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2C1

Produktdetails anti-ATM Antikörper

Bindungsspezifität: AA 2577-3056

Spezifität: Recombinant protein expressed in E. coli corresponding to amino acids 2577-3056.

Aufreinigung: Protein G purified

Immunogen: Recombinant human ATM.

Type of Immunogen: Recombinant protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: IF, IHC, IHC-P (5 μg/mL), IP, WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4. Preservative free.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu ATM

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Andere Bezeichnung: ATM

Hintergrund: Name/Gene ID: ATM
Subfamily: PI3/PI4
Family: Protein Kinase

Synonyms: ATM, A-T mutated, ATA, ATC, ATD, ATE, AT mutated, Ataxia telangiectasia, ATDC, Serine-protein kinase ATM, AT1, Ataxia telangiectasia mutated, TEL1, TELO1

Gen-ID: 472

Pathways: p53 Signalweg, Apoptose, DNA Reparatur, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus