NOTCH3 Antikörper (APC)
Kurzübersicht für NOTCH3 Antikörper (APC) (ABIN2568400)
Target
Alle NOTCH3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein.
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Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- NOTCH3 (Notch 3 (NOTCH3))
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Andere Bezeichnung
- Notch3
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Hintergrund
- The HMN3-133 monoclonal antibody specifically reacts with mouse Notch3, a single-pass transmembrane protein. After binding with its ligand, Notch3 receptor undergoes cleavage resulting in a Notch intracellular domain (NICD) molecule that eventually activates transcription in the nucleus. It is expressed on Treg cells and adult smooth muscle arterial cells.
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Gen-ID
- 18131
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UniProt
- Q61982
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Pathways
- Notch Signalweg
Target
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