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CD44 Antikörper (APC-Cy7)

CD44 Reaktivität: Human, Maus FACS Wirt: Ratte Monoclonal IM7 APC-Cy7

Produktnummer ABIN2567719

Datenblatt (PDF)

Target Alle CD44 Antikörper anzeigen

CD44
Reaktivität
300

155

71

31

25

23

14

13

10

9

8

7

7

5

5

4

2

2

1

1

1

1

1

1
Human, Maus
Wirt
170

120

92

1

1
Ratte
Passende Sekundärantikörper
Klonalität
271

111

2
Monoklonal
Konjugat
173

43

31

23

17

7

6

6

6

5

5

4

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Dieser CD44 Antikörper ist konjugiert mit APC-Cy7
Applikation
280

152

89

78

72

69

57

45

40

30

27

15

9

7

6

6

5

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24).

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

IM7

Isotyp

IgG2b kappa

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.2 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD44

Andere Bezeichnung

CD44 (CD44 Produkte)

Hintergrund

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.

Gen-ID

960, 12505

UniProt

P16070, P15379

Pathways

Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling