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CD44 Antikörper (violetFluor™ 450)

CD44 Reaktivität: Human, Maus FACS Wirt: Ratte Monoclonal IM7 violetFluor™ 450
Produktnummer ABIN2567704
  • Target Alle CD44 Antikörper anzeigen
    CD44
    Reaktivität
    • 313
    • 152
    • 71
    • 31
    • 25
    • 22
    • 14
    • 13
    • 10
    • 9
    • 7
    • 7
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 180
    • 119
    • 92
    • 1
    • 1
    • 1
    Ratte
    Klonalität
    • 281
    • 110
    • 2
    Monoklonal
    Konjugat
    • 172
    • 43
    • 31
    • 23
    • 17
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD44 Antikörper ist konjugiert mit violetFluor™ 450
    Applikation
    • 290
    • 150
    • 87
    • 77
    • 70
    • 70
    • 53
    • 43
    • 40
    • 30
    • 26
    • 15
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24).
    Aufreinigung
    The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
    Klon
    IM7
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product CD44 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
    Lagerung
    4 °C
    Informationen zur Lagerung
    The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
  • Target
    CD44
    Andere Bezeichnung
    CD44 (CD44 Produkte)
    Hintergrund
    The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.BG Violet 450 conjugate is an alternative to the Pacific Blue, eFluor 450, or BD Horizon V450 dyes. It is excited by the violet (405 nm) laser, with a peak emission of 450nm.
    Gen-ID
    960, 12505
    UniProt
    P16070, P15379
    Pathways
    Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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