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CD44 Antikörper

CD44 Reaktivität: Human, Maus FACS, WB, IHC, IP, Func Wirt: Ratte Monoclonal IM7 unconjugated

Produktnummer ABIN2567698

Datenblatt (PDF)

Target Alle CD44 Antikörper anzeigen

CD44
Reaktivität
299

154

71

31

25

23

14

13

10

9

8

7

7

5

5

4

2

2

1

1

1

1

1

1
Human, Maus
Wirt
170

120

91

1

1
Ratte
Passende Sekundärantikörper
Klonalität
270

111

2
Monoklonal
Konjugat
172

43

31

23

17

7

6

6

6

5

5

4

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
Dieser CD44 Antikörper ist unkonjugiert
Applikation
279

151

88

77

72

69

57

45

40

30

27

14

9

7

6

6

5

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)

Spezifität

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24).

Aufreinigung

The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Klon

IM7

Isotyp

IgG2b kappa

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CD44 Reaktivität: Human WB, IHC (p) Wirt: Maus Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

0.5 mg/mL

Buffer

Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung

4 °C

Informationen zur Lagerung

The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
Target

CD44

Andere Bezeichnung

CD44 (CD44 Produkte)

Hintergrund

The IM7 monoclonal antibody specifically reacts with all the isoforms and both alloantigens of the CD44 glycoprotein (Pgp-1, Ly-24). CD44 is expressed on hematopoietic and non-hematopoietic cells, bone marrow myeloid cells, memory T lymphocytes, periphery activated B cells, CD4+ T lymphocytes, and CD8+ T lymphocytes. The periphery B and T lymphocytes upregulate the expression of CD44. CD44 binds to hyaluronan molecules, acting as an adhesion molecule.The IM7 antibody inhibits collagen-induced arthritis in DBA/1 mice, prevents central nervous system inflammation associated with experimental autoimmune encephalomyelitis, but exacerbates the experimental autoimmune thyroiditis in CBA/J mice. The IM7 antibody also cross-reacts with dog, human, pig, horse, cat, and cow leukocytes.

Gen-ID

960, 12505

UniProt

P16070, P15379

Pathways

Glycosaminoglycan Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling