CD3 Antikörper (FITC)

Produktnummer ABIN2567522

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD3 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD3 Antikörper (FITC) (ABIN2567522)

Target: CD3

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: UCHT1

Produktdetails anti-CD3 Antikörper (FITC)

Spezifität: The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund: The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.

Gen-ID: 916

UniProt: P07766

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway