CD3 Antikörper
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- Target Alle CD3 Antikörper anzeigen
- CD3
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD3 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Functional Studies (Func), Immunofluorescence (IF), Western Blotting (WB)
- Spezifität
- The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex.
- Aufreinigung
- The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.
- Klon
- UCHT1
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD3 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 2 mg/mL
- Buffer
- Phosphate-buffered aqueous solution, ph7.2.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The product should be stored undiluted at 4°C. Do not freeze.
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- Target
- CD3
- Andere Bezeichnung
- CD3 (CD3 Produkte)
- Hintergrund
- The UCHT1 monoclonal antibody specifically reacts with the ε chain of the CD3/T lymphocyte antigen receptor complex. The CD3 complex contains γ, δ, and ε chains, and it is part of the TCR complex, expressed by all mature T lymphocytes and by the thymocyte lineage. CD3 enhances the antigen recognition by signal transduction. Unlike HIT3a, another specific antibody of CD3, the UCHT1 antibody can stain both the surface and intracellular CD3ε. The immobilized UCHT1 can cross-link with the TCR complex, enhancing cellular activation and proliferation.
- Gen-ID
- 916
- UniProt
- P07766
- Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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