CD3 Antikörper (PE)

Produktnummer ABIN2567486

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch CD3 in FACS. Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für CD3 Antikörper (PE) (ABIN2567486)

Target: CD3

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD3 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: 17A2

Produktdetails anti-CD3 Antikörper (PE)

Spezifität: The 17A2 monoclonal antibody specifically reacts with the MouseT lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation.

Aufreinigung: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Lagerung: 4 °C

Informationen zur Lagerung: The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.

Details zu CD3

Target: CD3

Andere Bezeichnung: CD3

Hintergrund: The 17A2 monoclonal antibody specifically reacts with the MouseT lymphocytes receptor (TCR) associated CD3 complex, resulting in cellular activation and proliferation. CD3 is expressed by thymocytes and mature lymphocytes, and contains γ, δ, and ε subunits, involved in the assembly, trafficking, and surface expression of T-cell receptor complex. The interaction between the T lymphocytes and the 17A2 antibody can be blocked by the 145-2C11 anti-CD3e antibody, demonstrating that the 17A2 antibody recognizes the CD3 ε chain.

Gen-ID: 12501

UniProt: P22646

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway